Dr. Feinberg has authored a research article entitled “Controlling the contractile strength of engineered cardiac muscle by hierarchal tissue architecture” in the journal Biomaterials. This article describes the use of engineered, matrix encoded boundary conditions to control the assembly and contractile function of engineered heart muscle. The results have important implications in how to maximize the physiologic function of engineered tissues.
This video shows examples of how controlling the alignment of the heart muscle cells can dramatically increase the contractile force these engineered tissues generate.
