{"id":1724,"date":"2021-07-21T12:44:00","date_gmt":"2021-07-21T19:44:00","guid":{"rendered":"https:\/\/regenerativebiomaterials.com\/?p=1724"},"modified":"2021-10-20T13:00:57","modified_gmt":"2021-10-20T20:00:57","slug":"dynamic-loading-of-human-engineered-heart-tissue-enhances-contractile-function-and-drives-a-desmosome-linked-disease-phenotype","status":"publish","type":"post","link":"https:\/\/regenerativebiomaterials.com\/wordpress\/?p=1724","title":{"rendered":"Dynamic Loading of Human Engineered Heart Tissue Enhances Contractile Function and Drives a Desmosome-linked Disease Phenotype"},"content":{"rendered":"\n<figure class=\"wp-block-video\"><video controls src=\"https:\/\/regenerativebiomaterials.com\/wordpress\/wp-content\/uploads\/2021\/10\/EHT-Website.mp4\"><\/video><\/figure>\n\n\n\n<p><strong>Jacqueline M. Bliley<\/strong>, Mathilde C. S. C. Vermeer, Rebecca M. Duffy, Ivan Batalov, Duco Kramer, Joshua W. Tashman, Daniel J. Shiwarski, Andrew Lee, Alexander S. Teplenin, Linda Volkers, Brian Coffin, Martijn F. Hoes, Anna Kalmykov, Rachelle N. Palchesko, Yan Sun, Jan D. H. Jongbloed, Nils Bomer, Rudolf A. de Boer, Albert J. H. Suurmeijer, Daniel A. Pijnappels, Maria C. Bolling, Peter van der Meer*, and  Adam W. Feinberg are co-authors on our recent publication in <strong><em>Science Translational Medicine <\/em><\/strong>titled &#8220;Dynamic loading of human engineered heart tissue enhances contractile function and drives a desmosome-linked disease phenotype.&#8221; <a href=\"https:\/\/www.science.org\/doi\/10.1126\/scitranslmed.abd1817\">Here<\/a>, we use a novel dynamic engineered heart tissue (dyn-EHT) system to model arrhythmogenic cardiomyopathy. <br><br><strong><a href=\"https:\/\/www.science.org\/doi\/10.1126\/scitranslmed.abd1817\">Read the article in Science Translational Medicine.<\/a><\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator is-style-wide\"\/>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Jacqueline M. Bliley, Mathilde C. S. C. Vermeer, Rebecca M. Duffy, Ivan Batalov, Duco Kramer, Joshua W. Tashman, Daniel J. Shiwarski, Andrew Lee, Alexander S. Teplenin, Linda Volkers, Brian Coffin, Martijn F. Hoes, Anna Kalmykov, Rachelle N. Palchesko, Yan Sun, Jan D. H. Jongbloed, Nils Bomer, Rudolf A. de Boer, Albert J. H. Suurmeijer, Daniel &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/regenerativebiomaterials.com\/wordpress\/?p=1724\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Dynamic Loading of Human Engineered Heart Tissue Enhances Contractile Function and Drives a Desmosome-linked Disease Phenotype&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3,5],"tags":[],"_links":{"self":[{"href":"https:\/\/regenerativebiomaterials.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/1724"}],"collection":[{"href":"https:\/\/regenerativebiomaterials.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/regenerativebiomaterials.com\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/regenerativebiomaterials.com\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/regenerativebiomaterials.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1724"}],"version-history":[{"count":6,"href":"https:\/\/regenerativebiomaterials.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/1724\/revisions"}],"predecessor-version":[{"id":1738,"href":"https:\/\/regenerativebiomaterials.com\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/1724\/revisions\/1738"}],"wp:attachment":[{"href":"https:\/\/regenerativebiomaterials.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1724"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/regenerativebiomaterials.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1724"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/regenerativebiomaterials.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1724"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}