Congratulations to TJ Hinton, who in recognition of his outstanding performance during the past year as an MS student has been awarded a stipend by the BME Department to support his research in Summer 2012.
TJ Wins Summer Research Fellowship
Publication: Controlling the contractile strength of engineered cardiac muscle by hierarchal tissue architecture
Dr. Feinberg has authored a research article entitled “Controlling the contractile strength of engineered cardiac muscle by hierarchal tissue architecture” in the journal Biomaterials. This article describes the use of engineered, matrix encoded boundary conditions to control the assembly and contractile function of engineered heart muscle. The results have important implications in how to maximize the physiologic function of engineered tissues.
This video shows examples of how controlling the alignment of the heart muscle cells can dramatically increase the contractile force these engineered tissues generate.
Dr. Palchesko Presents at ARVO
Dr. Rachelle Palchesko presented her working on the in vitro expansion of corneal endothelial cells at the 2012 meeting of the Association for Research in Vision and Ophthalmology (ARVO) in Ft Lauderdale.
Bottom-Up Engineering of the Extracellular Matrix
Dr. Feinberg gave a presentation entitled “Bottom-Up Engineering of the Extracellular Matrix” at the 7th Symposium on Biologic Scaffolds for Regenerative Medicine held in Napa, CA on April 28, 2012.
Drs. Feinberg and Palchesko discuss our latest research on the Regenerative Medicine Today Podcast
“Regenerative Medicine Today welcomes Adam Feinberg, PhD and Rachelle Palchesko, PhD. Dr. Feinberg is the principal investigator of the Regenerative Biomaterials and Therapeutics Group at Carnegie Mellon University. Dr. Palchesko is a Postdoctoral Research Fellow in the group. Drs. Feinberg and Palchesko discuss the development of basement membranes and the regeneration of corneal endothelium.”
Welcome to our new MS graduate student Amrita!
Welcome to Amrita Sahu, who is joining our group as a BME MS-track graduate student. Amrita will be working on ECM protein scaffolds.
Drs. Palchesko and Feinberg Discuss Bioengineering the Corneal Endothelium
Under the Fox Center OTERO program, Rachelle Palchesko, PhD and her scientific mentors (Adam W. Feinberg, PhD-Carnegie Mellon University, and James L. Funderburgh, PhD-University of Pittsburgh ) are researching the regeneration of the corneal endothelium, the posterior layer of the cornea. When this essential tissue is affected by disease or trauma, the corneal transparency is reduced and vision decreases.
To learn more about Dr. Palchesko’s research project, please view the following videos:
OTERO Project part A: Rachelle and Adam talk about the Fox Center Otero project on regenerating the corneal endothelium. Find out about the risks and rewards, the strategic view and the objectives associated with seed funding a multidisciplinary approach in eye regeneration.
OTERO Project part B: Rachelle and Adam talk about regenerating the corneal endothelium and how is this project different from traditional approaches. Learn about their research, the areas they try to understand and the instruments they use in their Lab.
The Center for the Mechanics and Engineering of Cellular Systems is Established at CMU
Prof. Feinberg and the Regenerative Biomaterials and Therapeutics Group are founding members of the newly formed Center for the Mechanics and Engineering of Cellular Systems at CMU.
“The vision of the center is that a comprehensive understanding of the input and output of mechanical signals inside living cells, and between cells and the environment is essential in numerous areas. Significant improvements in the prevention and treatment of cancer, birth defects, and aging, as well as novel applications such as engineered tissues, nutrition and biological nanomachines, may be achieved by manipulating mechanical interactions in integrated biological systems at the molecular, cellular, and multi-cellular scales. Through leveraging the long-standing transdisciplinary culture of Carnegie Mellon University, the Center is built upon strengths in engineering, physics, life sciences, and computation across multiple departments and colleges.”
Welcome to our new graduate students Rebecca and TJ
A warm welcome to two graduate students that have joined the Regenerative Biomaterials and Therapeutics group this semester. Rebecca Duffy from Virginia Commonwealth University is a PhD-track BME student who will be working on muscle tissue engineering. TJ Hinton from Purdue University is an MS-track BME student who will be working on new fabrication strategies for 3-D tissue engineering scaffolds.
Publication: Engineered tissue grafts: opportunities and challenges in regenerative medicine
Dr. Feinberg has authored a review article entitled “Engineered tissue grafts: opportunities and challenges in regenerative medicine” in the journal Wiley Interdisciplinary Reviews: Systems Biology and Medicine.